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The activation of the Nrf2 (nuclear factor erythroid-derived 2)/ARE (antioxidant response elements) pathway is likely a principal and underlying mechanism of hormesis, which can limit age-related damage, numerous disease processes progression, and induction of toxicities due to chemicals and radiations ( 6 Synergic anticancer effect of sulforaphane in combination with other chemotherapeutic agents Sulforaphane can also be used with conventional cancer treatments to achieve an enhanced effect

Clinical Insight Clinicians should anchor gut health assessment in a multidomain framework that includes patient-reported symptoms and quality-of-life impact, recognizing that omics-based stool tests are not yet ready to guide routine clinical decisions

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While this sounds beneficial for healing, angiogenesis is directly implicated in tumour growth, cancer proliferation and inflammatory diseases